Introduction
The purpose of this study is to allow for deep and broad phenotyping of persons with clinically-meaningful fatiguing symptoms, regardless of physiologic or pathologic condition. The protocol is designed as an exploratory multi-stage study. The study population will consist of up to 672 persons with or without clinically-meaningful fatigue. Approximately 20 will be enrolled in the technical development substudy to refine the neuroimaging techniques used in this study.
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